A mitochondrial phosphatase required for cardiolipin biosynthesis: the PGP phosphatase Gep4
نویسندگان
چکیده
منابع مشابه
A mitochondrial phosphatase required for cardiolipin biosynthesis: the PGP phosphatase Gep4.
Cardiolipin (CL), a unique dimeric phosphoglycerolipid predominantly present in mitochondrial membranes, has pivotal functions for the cellular energy metabolism, mitochondrial dynamics and the initiation of apoptotic pathways. Perturbations in the mitochondrial CL metabolism cause cardiomyopathy in Barth syndrome. Here, we identify a novel phosphatase in the mitochondrial matrix space, Gep4, a...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 2010
ISSN: 0261-4189,1460-2075
DOI: 10.1038/emboj.2010.98